Lack of evidence for distinct hepatitis C virus variants associated with cryoglobulin

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Cryoglobulin Test and Cryoglobulinemia Hepatitis C-Virus Related

Cryoglobulins are immunoglobulins that precipitate in serum at temperatures below 37°C and resolubilize upon warming. The clinical syndrome of cryoglobulinemia usually includes purpura, weakness, and arthralgia, but the underlying disease may also contribute other symptoms. Blood samples for cryoglobulin are collected, transported, clotted and spun at 37°C, before the precipitate is allowed to ...

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Existence of distinct GB virus C/hepatitis G virus variants with different tropism.

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The Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran

Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...

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Hepatitis C virus (HCV) infection: serum rheumatoid factor activity and HCV genotype correlate with cryoglobulin clonality.

Chronic hepatitis C virus (HCV) infection has only recently been recognized as the leading cause of mixed cryoglobulinemia.1,2 Rheumatoid factor B cells are part of the normal repertoire and significant titers of rheumatoid factors (RF) are induced during normal antiviral or antibacterial immune responses. Under the pressure of chronic antigen stimulation, RF repertoire is remodeled, and progre...

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ژورنال

عنوان ژورنال: Hepatology

سال: 1999

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.510290212